白芳，女，漢族，畢業(yè)于吉林大學(xué)，現(xiàn)任南開(kāi)大學(xué)藥學(xué)院副教授，主要研究微生物與生化藥物。

中文名

白芳

性別

女

國(guó)籍

中國(guó)

職業(yè)

教師

所屬行業(yè)

教育

人物經(jīng)歷

1999年9月至2003年7月就讀于吉林大學(xué)生命科學(xué)學(xué)院生物制藥專業(yè)，2003年9月考入南開(kāi)大學(xué)微生物學(xué)系攻讀研究生，2008年7月獲得理學(xué)博士學(xué)位后留校任教。

研究方向

微生物藥物高通量篩選，基于結(jié)構(gòu)基因或蛋白的藥物分子設(shè)計(jì)。

主要貢獻(xiàn)

1. Limei Ren, Xiaofang Cao, Peng Geng, Fang Bai*, Gang Bai. Study of the inhibition of two human maltase-glucoamylases catalytic domains by different α-glucosidase inhibitors. Carbohydrate Research, 2011, 346: 2688-2692.

2. Peng Meng, Yuanqiang Guo, Qi Zhang, Jie Hou, Fang Bai*, Peng Geng, Gang Bai. A novel amino-oligosaccharide isolated from the culture of Streptomyces strain PW638 is a potent inhibitor of α-amylase. Carbohydrate Research, 2011, 346: 1898-1902.

3. Xiaohong Qin, Limei Ren, Xue Yang, Fang Bai, Lele Wang, Peng Geng, Gang Bai, Yuequan Shen. Structures of human pancreatic a-amylase in complex with acarviostatins: Implications for drug design against type II diabetes. Journal of Structural Biology, 2011, 174: 196-202.

4. Limei Ren, Xiaohong Qin, Xiaofang Cao, LeleWang, Fang Bai, Gang Bai, Yuequan Shen. Structural insight into substrate specificity of human intestinal maltase-glucoamylase. Protein & Cell, 2011, 2(10): 827–836.

5. Fang Bai, Haijin Xu, Qi Zhang, Xizhen Qi, Rui Mou, Gang Bai, Mingqiang Qiao. Functional characterization of pfm in protein secretion and lung infection of Pseudomonas aeruginosa. Canadian Journal of Microbiology, 2011, 57: 829-837.

6. Rui Mou, Fang Bai, Qiaonan Duan, Xuehan Wang, Haijin Xu, Yanling Bai, Xiuming Zhang, Shouguang Jin, Mingqiang Qiao. Mutation of pfm affects the adherence of Pseudomonas aeruginosa to host cells and the quorum sensing system. FEMS Microbiology Letters, 2011, 324(2):173-80.

7. Peng Geng, Gang Bai, Xiansheng Meng, Fang Bai, Guoan Luo. Screening for metabolites of acarviostatin family aminooligosaccharides in rats using ultraperformance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 2009, 50: 917–923.

8. Fang Bai, Yingli Li, Haijing Xu, Huiming Xia, Tengfei Yin, Hongming Yao, Lu Zhang, Xiuming Zhang, Yanling Bai, Shouguang Jin and Mingqiang Qiao. Identification and functional characterization of pfm, a novel gene involved in swimming motility of Pseudomonas aeruginosa. Gene, 2007, 401: 19-27.

先后主持南開(kāi)大學(xué)青年教師研究資助項(xiàng)目、天津市自然科學(xué)基金、國(guó)家自然科學(xué)基金，并參與國(guó)家高技術(shù)研究發(fā)展計(jì)劃(863計(jì)劃)等項(xiàng)目。