吳德群，東華大學(xué)紡織學(xué)院副教授。

畢業(yè)院校

武漢大學(xué)

任職單位

東華大學(xué)紡織學(xué)院

職稱

副教授

個人簡介

2004 -2009 武漢大學(xué)碩博連讀理學(xué)博士；

2009 新加坡南洋理工大學(xué)博士后；

2010-2013美國康奈爾大學(xué)博士后；

2013- 東華大學(xué)紡織學(xué)院副教授；

研究方向

生物醫(yī)用紡織；

材料天然纖維改性；

生物可降解材料自組裝及其藥物緩釋載體；

納米生物傳感器；

榮譽(yù)及獲獎情況

2014年上海市浦江人才計(jì)劃

2014年紡織工業(yè)聯(lián)合會科學(xué)技術(shù)進(jìn)步一等獎

科研項(xiàng)目

2014年上海市浦江人才計(jì)劃

代表性論文

Wu DQ, Sun YX, Xu XD, Cheng SX, ZhangXZ, and Zhuo RX. Biodegradable and pH-sensitive hydrogels for cell encapsulation and controlled drug release. Biomacromolecules 2008,9:1155-1162.

Wu DQ, Wang T, Lu B, Xu XD, Cheng SX, Jiang XJ, ZhangXZ, Ren-Xi Zhuo. Fabrication of supramolecular hydrogels for drug delivery and stem cell encapsulation. Langmuir 2008,24:10306-10312.

Wu DQ, Lu B, Chang C, Chen CS, Zhang YY, Cheng SX, Zhang XZ, Zhuo RX. Galactosylated fluorescent labeled micelles as a liver targeting drug carrier. Biomaterials. 2009,30:1363-1371.

Wu DQ, Qiu F, Wang T, Zhang XZ, Zhuo RX. Towards development of partially biodegradable and injectable thermoresponsive hydrogels for potential biomedical applications. ACS Applied materials & interfaces. 2009,1:319-327.

Wu DQ, Li ZY, Fan JJ, Cheng SX, Jiang XJ, ZhangXZ, Ren-Xi Zhuo. Porphyrin and Galactosyl Conjugated Micelles for Targeting Photodynamic Therapy. Pharmaceutical Research, 2010, 27:187-199.

Dequn Wu, Jun Wu, Chi-Chang Chu. A Novel Family of Biodegradable HybridHydrogels from Arginine-based Poly(ester amide) and Hyaluronic AcidPrecursors. Soft matter. 2013, DOI: 10.1039/c3sm27820d.

Jun Wu, Dequn Wu, Martha A. Mutschler, and Chih-Chang Chu, Cationic Hybrid Hydrogels from Amino Acid-Based Poly (ester amide): Fabrication, Characterization, and Biological Property.Advanced Functional Materials. 2012,22,3815-3823.

Xiao-Hong Qin, De-Qun Wu, Chih-Chang Chu. Dual functions of polyvinyl alcohol (PVA): fabricating particles and electrospinningnanofibers applied incontrolled drug release. Journal of Nanoparticle Research. 2013,15:1395-1409.

Lu B,Wu DQ,Zheng H,Quan CY,Zhang XZ, Zhuo RX.Galactosyl conjugated N-succinyl-chitosan-graft-polyethylenimine for targeting gene transfer.Molecular Biosystems, 2010, 6, 2529-2538.

Xun W, Wu DQ, Li ZY, Wang HY, Huang FW, Cheng SX, Zhang XZ, ZhuoRX.Peptide-Functionalized Thermo-Sensitive Hydrogels for Sustained Drug Delivery. Macromolecular bioscience. 2009, 12, 1219-1226.

Quan CY, Wu DQ, Chang C, Zhang GB, ChengSX, Zhang XZ, Zhuo RX. Synthesis of thermo-sensitive micellar aggregates self-assembled from biotinylated PNAS-b-PNIPAAm-b-PCL triblock copolymers for tumor targeting. Journal of Physical Chemistry C. 2009, 113:11262-11267.

Wang T, Wu DQ, Jiang XJ, Li XY, Zhang JF, Zheng ZB, Jiang H, Huang CX, Zhang XZ. Novel thermosensitive hydrogel injection inhibits post-infarct ventricle remodeling. European Journal of Heart Failure. 2009, 11:14-19.

Lu B, Wang CF, Wu DQ, Li C, Zhang XZ, Zhuo RX. Chitosan based oligoamine polymers:synthesis, characterization, and gene delivery. Journal of Controlled Release. 2009,137:54-62。

Hu CH, Zhang L, Wu DQ, Cheng SX , Zhang XZ, Zhuo RX. Heparin-modified PEI encapsulated in thermosensitive hydrogels for efficient gene delivery and expression. Journal of materials chemistry. 2009,19:3189-3197.

Qin XH, Wu DQ. Effect of different solvents on poly(caprolactone) (PCL)electrospun nonwoven membranes. Journal of Thermal Analysis andCalorimetry, 2011, 102, 1-7.

Chang C, Wei H, Feng J, Wang ZC, Wu XJ, Wu DQ, Cheng SX, Zhang XZ, and ZhuoRX.Temperature and pH Double Responsive Hybrid Cross-Linked Micelles Based on P(NIPAAm-co-MPMA)-b-P(DEA): RAFT Synthesis and “Schizophrenic” Micellization. Macromolecules 2009,42:4838-4844.

Zhang J, Xu XD, Wu DQ, Zhang XZ, Zhuo RX. Synthesis of thermosensitiveP(NIPAAm-co-HEMA)/cellulose hydrogels via “click” chemistry. Carbohydrate Polymers. 2009,77:583–589.

Qiu F, Feng J, Wu DQ, Zhang XZ, Zhuo RX. Nanosized Micelles Self-Assembled from amphiphilic dextran-graft-methoxypolyethylene glycol/poly(epsilon-caprolactone) copolymers. European Polymer Journal. 2009, 45:1024-1031.

Wang T, Jiang XJ, Tang QZ, Li XY, Lin T, Wu DQ, Zhang XZ, Okello E. Bone marrow stem cells implantation with a-cyclodextrin/MPEG–PCL–MPEG hydrogel improves cardiac function after myocardial infarction. ActaBiomaterialia. 2009, 5: 2939-2944.

Wei H, Wu DQ, Li Q, Cheng SX, ZhangXZ, and Zhuo RX. Preparation of shell cross-linked thermoresponsive hybrid micelles as well as hollow spheres based on P(NIPAAm-co-HMAAm-co-MPMA)-b-PCL. Journal of physical chemistry C. 2008, 112:15329.

Li XY, Wang T, Jiang XJ, Lin T, Wu DQ, Zhang XZ. Injectable Hydrogel Helps Bone Marrow-Derived Mononuclear Cells Restore Infarcted Myocardium. Cardiology. 2010, 115,194-199.

Jun Wu, Xin Zhao, Dequn Wu and Chih-Chang Chu.Development of a biocompatible and biodegradable hybrid hydrogel platform for sustained release of ionic drugs. J. Mater. Chem. B, 2014,2, 6660-6668.

專利

張先正，吳德群，卓仁喜。溫度敏感性生物可降解水凝膠的制備與應(yīng)用。專利號：200810048486.0

Chu Chih-Chang, Wu De-Qun. Advanced Generation Lysine-based Multifunctional Poly(ester amide)s. D-5447

Chu Chih-Chang, Wu De-Qun. Peptide-based Poly(ester amide)s D-5400

Chu Chih-Chang, Wu De-Qun, He Mingyu. Polysaccharide-based hydrogels and hybrid hydrogels and precursors thereof, methods of making same, and uses thereof. Publication number: WO2013/181566

Chu Chih-Chang, Qin Xiao-Hong, Wu De-Qun. Fabrication of Synthetic Biodegradable Amino Acid Poly(ester amide)s Nanoparticles . D-5597