鄭化（鄭化）

人物簡介

性別：男

出生年月：1965年9月

學位：博士

鄭化

1982-1986年北京師范大學化學系化學專業(yè)學習，獲理學學士學位

1994-1996年原武漢汽車工業(yè)大學高分子化工專業(yè)學習、獲工學碩士學位

1998-2001年武漢大學環(huán)境科學專業(yè)天然高分子研究方向?qū)W習、獲工學博士學位

研究領域

1、藥用中間體合成與工藝

2、藥用高分子合成與生物學評價

3、現(xiàn)代藥物劑型與制劑新技術

科研項目

1、pH敏感羧甲基甲殼糖納米粒的制備及其結腸定位給藥系統(tǒng)研究, 國家自然科學基金（50503019）

2、由甲殼動物廢棄物制備2-脫氧-D-葡萄糖工藝研究與產(chǎn)品開發(fā)，浙江省重大科技關項目(2004E30015)

3、大孔樹脂用于中藥生產(chǎn)的技術標準研究及中試平臺建設，湖北省重大科技攻關項目（2006AA302A05）

4、結腸用羧甲基殼聚糖緩控釋凝膠新輔料開發(fā)，湖北省重點科技攻關項目（2006AA301B17）

5、殼聚糖基質(zhì)仿生皮膚的研究與開發(fā)，湖北省重點科技攻關項目( 2003AA303B09)

6、醫(yī)用納米HAP粉體材料產(chǎn)業(yè)化開發(fā)研究，湖北省重點科技攻關項目( 2003AA303B01)

7、藥物新劑型及相關技術開發(fā)，湖北省重點科技攻關項目( 2007AA301B12)

8、高性能水性環(huán)氧防腐涂料的研究開發(fā)及產(chǎn)業(yè)化，廣東省教育部產(chǎn)學研結合項目（2008B090500176）

9、基于殼聚糖衍生物的智能釋藥肝靶向納米傳遞系統(tǒng)的構建，武漢市重大人才專項（20091j0001） ? .

國家基礎化學教學指導委員會委員、中國化學會甲殼素研究會副主任委員、湖北省生物工程學會常務理事、湖北省化學化工學會理事、武漢理工大學學報編委。

2007年發(fā)表的論文

1. Yihua Yin , Xingmin Ji, Hui Dong, Yi Ying, Hua Zheng. Study of the swelling dynamics with overshooting effect of hydrogels based on sodium alginate-g-acrylic acid, Carbohydrate Polymers

2. Hua Zheng, Ziyan Zhou, Yun Chen, Jin Huang, Fuliang Xiong, “pH-Sensitive Alginate / Soy Protein Microspheres as Drug Transporter”, Journal of Applied Polymer Science, 2007, 106, 1034-1041.

3. Xu Yong Mei, Zhan Chang You, Fan Li Hong, Wang Le, Zheng Hua. Preparation of dual crosslinked alginate-chitosan blend gel beads and in vitro controlled release in oral site-specific drug delivery system. International Journal of Pharmaceutics. 2007, 336 (2): 329-337

4. Zheng Hua, Ai Fu Jin, Wei Ming, et al. Thermoplastic soy protein nanocomposites reinforced by carbon nanotubes. Macromolecular Materials and Engineering, 2007, 292 (6): 780-788

5. Zheng Hua; Qin Huiyu, et al. Novel dual crosslinked complex gel bead based on carboxymethyl chitosan/alginate for oral delivery of protein drugs. Polymeric Materials: Science & Engineering, 2007, 96:681-682

6. Zhu Yan, Sun Duo Xian, Zheng Hua, et al. Improvement in properties of epoxy-based electrophoretic coating by silica/polyurethane nanocomposites. Journal of Materials Science, 2007, 42 (2): 545-550

7. He Guanghua, Zheng Hua, Fu Zhongjun. Preparation and characterization of poly(vinyl alcohol)/carboxymethyl chitosan hydrogels obtained by freezing/ thawing techniques. Polymeric Materials: Science & Engineering, 2007, 96, 367-368

8. He Guanghua, Zheng Hua. Effect of NaCl on properties of freeze/thawed hydrogels composed of poly(vinyl alcohol) and chitosan. Polymeric Materials: Science & Engineering, 2007, 96, 342-343

9. Ai Fu Jin, Zheng Hua, Wei Ming, et al. Soy protein plastics reinforced and toughened by SiO2 nanoparticles. Journal of Applied Polymer Science, 2007,105 (3): 1597-1604

10. Fan Li Hong, Zheng Hua, Xu Yong Mei, et al. Preparation and properties of chitosan/konjac glucomannan blend fibers. Journal of Macromolecular Science Part A-Pure and Applied Chemistry, 2007, 44: 439-443

11. Zheng Hua; Qin Huiyu, et al. Preparation and characterization of a novel carboxymethyl chitosan hydrogel for drug controlled release. Polymeric Materials: Science & Engineering, 2007, 96:552-553

12. Zhu Yan, Chen Yu, Zhang, Lianmeng; Zheng, Hua. Preparation of polystyrene/polyurethane core/shell nanoparticles by emulsion polymerization of styrene using anionic polyurethane as the surfactant. Polymeric Materials: Science & Engineering, 2007, 97 763-764

13. Zheng Hua, Zou X. Q., He, Fei. Preparation and characterization of the hydrogel of carboxymethyl chitin grafted acrylic acid. Polymeric Materials: Science & Engineering, 2007, 97: 761-762

14. He Guanghua, Zheng Hua, Zhao Runxiang. Swelling kinetics of physically crosslinked carboxymethyl chitosan/poly(vinyl alcohol) hydrogels. Polymeric Materials: Science & Engineering, 2007, 97:755-756

15. Yi Ying, Ye Fayin, Chou Huang, Zheng Hua, Guan Jianguo, Li, Bing. Studies on properties of core-shell acrylic-polyurethane emulsion modified by epoxy resin. Polymeric Materials: Science & Engineering, 2007, 97:735-737

16. Xu Yongmei, Wang Le, Zhan Changyou, Zheng, Hua. Preparation and performance research of carboxymethyl chitin/chitosan sponge. Polymeric Materials: Science & Engineering, 2007, 97:733-734

17. Ji Xingmin, Yin Yihua, Gao, Hui, Dong Yuxiang, Zheng Hua. Study of swelling kinetics of sodium alginate-graft-acrylic acid hydrogels. Polymeric Materials: Science & Engineering, 2007, 97:574-575

18. Gao Yuxiang, Ji Xingmin, Yin Yihua, Dong, Hui, Zheng Hua. Study of poly(N-isopropylacrylamide), poly(methacrylic acid), and their copolymers for oral colon-specific drug delivery. Polymeric Materials: Science & Engineering, 2007, 97:572-573

19. Dong Hui, Shao Yihua Yin, Xingmin Ji, Zheng, Hua. Study of the swelling dynamics of porous hydrogels based on poly(chitosan-g-acrylic acid) for oral colon targeting-drug delivery system. Polymeric Materials: Science & Engineering, 2007 , 97:520-521

20. Zhou Ziyan, Zheng, Hua, Yu Jiahui, Huang, Jin. Supramolecular nanoplatelets assembled from pluronic/cyclodextrin polyrotaxanes and reinforced soy protein-based nanocomposites thereof. Polymeric Materials: Science & Engineering, 2007 , 96:773-774

21. Zheng, Hua, Qin Huiyu, Zhang Chengsen, He Guanghua. Novel dual crosslinked complex gel bead based on carboxymethyl chitosan/alginate for oral delivery of protein drugs. Polymeric Materials: Science & Engineering, 2007, 96:681-682

22. Zheng, Hua, Qin, Huiyu, Huo Jintao, Xu Peihu, He Guanghua. Preparation and characterization of a novel carboxymethyl chitosan hydrogel for drug controlled release. Polymeric Materials: Science & Engineering, 2007, 96:552-553

23. Xu Yongmei, Zhan Changyou, Zheng Hua. Swelling and sustained drug release profiles of beads based on ionic crosslinkage. Polymeric Materials: Science & Engineering, 2007, 96:474-475

24. Xu Yongmei, Zhan, Changyou, Wang, Le, Zheng, Hua. Preparation and character of alginate and sodium carboxymethyl cellulose blend beads as floating drug delivery system. Polymeric Materials: Science & Engineering, 2007, 96: 443-445

25. Xu Yongmei, Zhan Changyou, Zheng Hua, Wang Le. Preparation and character of nanoparticles based on crosslinking between Ca2+ and carboxymethyl chitosan. Polymeric Materials: Science & Engineering, 2007, 96: 441-442

26. He Guanghua, Zheng Hua, Fu Zhongjun, Qin Hulyu. Preparation and characterization of poly(vinyl alchol)/carboxymethyl chitosan hydrogels obtained by freezing/thawing techniques. Polymeric Materials: Science & Engineering, 2007, 96: 367-368

27. He Guanghua, Zheng Hua, Chen Jianfeng, Qin Huiyu. Effect of NaCl on properties of freeze/thawed hydrogels composed of poly(vinyl alcohol) and chitosan. Polymeric Materials: Science & Engineering, 2007, 96: 342-344

28. 殷以華，董慧，季興敏，李國輝，姜建平，鄭 化. 羧甲基纖維素與丙烯酸接枝共聚凝膠的溶脹動力學及過溶脹平衡特性的研究. 化學學報.2007,65(3): 271-278

2006年發(fā)表論文

29. Zheng Hua; Liu Ya-li; Wei Ming. Synthesis and characterization of core-shell polyacrylate in emulsion polymerization via reverse ATRP，Polymer Preprints，2006, 47(2), 943-944

30. Zheng Hua; He Fei. Synthesis and pH sensitivity of 6-caboxymethyl chitin-based microsphere，Polymeric Materials: Science & Engineering, 2006, 95:415-417

31. Zheng Hua; Qin Huiyu，Preparation and characterization of dialdehydestarch- crosslinked carboxymethyl chitosan/gelatin hydrogel，Polymeric Materials: Science & Engineering, 2006, 95: 730-731

32. Zheng Hua, Du Yu Min, Yu Jia Hui, et al. Preparation and characterization of chitosan/poly(vinyl alcohol) blend fibers. Journal of Applied Polymer Science, 2001, 80 (13): 2558-2565

33. Zheng Hua, Du Yu Min. Preparation and characterization of chitosan/gelatin blend fibers. Polymeric Materials: Science & Engineering, 2002, 87:265-266

34. Zheng Hua, Zhou Jin Ping, Du Yu Min, et al. Cellulose/chitin films blended in NaOH/urea aqueous solution. Journal of Applied Polymer Science, 2002, 86 (7): 1679-1683

35. Zheng Hua, Zhao Jing, Tan Zan’ao, et al. Preparation and anticoagulant activities of konjac glucomannan sulfate. Polymeric Materials: Science & Engineering, 2005, 93,538-539

36. Zheng Hua. Preparation and characterization of SiO2/chitosan hybrid films. Polymeric Materials: Science & Engineering, 2004, 91:27-28

37. Zheng Hua, He Guanghua, Xu Yongmei. Characterization and controlled release of chitosan/poly(vinyl alcohol) microspheres. Polymeric Materials: Science & Engineering, 2004, 91,1011-1012

38. Zheng Hua, Tan Zan’ao, et al. Morphology and properties of soy protein plastics modified with chitin. Journal of Applied Polymer Science, 2003, 90 (13): 3676-3682

39. Zheng Hua, Tan Zan’ao, et al. Preparation of chitosan/gelatin composite fibers and their biodegradability. Key Engineering Materials, 2003, 249: 437-440

40. 鄭化，杜予民，余家會，肖玲. N-酰基殼聚糖的制備及取代度控制的研究. 武漢大學學報(自然科學版) 2000，46（6）：685-688

41. 鄭化，杜予民，余家會. 殼聚糖/聚乙烯醇共混纖維的結構與性能. 武漢大學學報(自然科學版) 2000,46(2): 187-190

42. 鄭化，杜予民. 纖維素/羧甲基殼聚糖共混膜結構與抗菌性能. 高分子材料科學與工程. 2002,18(4): 124-128

43. 鄭化，杜予民，周金平，張俐娜。纖維素/甲殼素共混膜的結構表征與抗凝血性能. 高分子學報.2002,4: 525-529

44. 鄭化，杜予民. N-酰基殼聚糖的合成及膜的結構與性能. 武漢大學學報(理學版). 2002, 48(2): 197-200

45. 鄭化，杜予民，余家會，肖玲。交聯(lián)殼聚糖膜的制備及性能的研究。高等學?；瘜W學報,2000,21(5): 809-812

46. Du Yu Min, Zheng Hua, Yu Jia Hui, et al. Preparation and characterization of chitosan/poly(vinyl alcohol) blend fibers. Polymeric Materials: Science & Engineering, 2000

47. He Guanghua, Zheng Hua. Preparation and characterization of carboxymethyl chitosan/poly(vinyl alcohol) hydrogels. Polymeric Materials: Science & Engineering, 2006, 95, 1060-1061

48. He Guanghua, Zheng Hua. Effect of preparation methods on properties of chitosan/poly(vinyl alcohol) hydrogels. Polymeric Materials: Science & Engineering, 2006, 95, 913-914

49. 岳智洲，趙靜，鄭化. 2-氨基-四乙酰基-β-D-葡萄糖合成方法的改進. 武漢理工大學學報.2006,28(9): 24-26

50. 樊李紅，杜予民，鄭化，黃榮華，唐汝培. 海藻酸/明膠共混膜結構表征及性能. 武漢大學學報(理學版), 47(6): 712-716

51. 魏銘，黃進，艾福金，樊李紅，鄭化. 新型木質(zhì)素衍生物增強大豆蛋白塑料. 武漢理工大學學報.28(5): 57-59

52. 余家會，杜予民，鄭化. 尼龍1010 與殼聚糖共混膜的制備、表征及性能研究. 高分子材料科學與工程,2001,17(5):116-120

優(yōu)秀事跡

2007年鄭化被評為湖北高校優(yōu)秀共產(chǎn)黨員，優(yōu)秀事跡如下：

鄭化同志依據(jù)學校黨委的《院黨政領導班子工作職責、議事規(guī)則與工作制度》、《關于加強和改進處級領導班子和領導干部作風建設的實施意見》等文件，加強班子建設。領導班子成員團結合作、分工明確、相互尊重、相互協(xié)作，已經(jīng)組成了一個團結、和諧、奮進的領導班子。

在黨風廉政建設中，鄭化深入學習《江澤民論黨風廉政建設和反腐敗斗爭》、《“三個代表”重要思想反腐倡廉理論學習綱要》、《建立健全教育、制度、監(jiān)督并重的懲治和預防腐敗體學院實施綱要》、胡錦濤總書記在中央紀委第五次全會上的重要講話等文件，做到警鐘長鳴，貫徹落實黨中央有關文件精神，學院領導干部中沒有違紀腐敗事件發(fā)生。

鄭化志發(fā)展意識強，認真學習《武漢理工大學學院工作目標責任制考核實施細則》，采取措施狠抓學科建設、教師隊伍建設、教學建設、教學改革、科研工作等，取得了明顯的成效。2002年任化學工程學院院長至今，始終以集體利益為重，克服重重困難，默默奉獻，使學院的整體面貌產(chǎn)生了優(yōu)異的變化。2001年學院科研經(jīng)費為40萬，2005年則達到近400萬，基本上是每年翻一番。2003年獲得了2個碩士點，實現(xiàn)了學院碩士點零的突破，2005年達到了8個碩士點及1個工程碩士點，使學院學科建設發(fā)生了質(zhì)的飛躍。2001年學院教授4人，副教授10人，博士3人，2005年有教授11人，占現(xiàn)任教師比例的29.7%，副教授9人，占現(xiàn)任教師比例的24.3%；教授、副教授共計占現(xiàn)任教師比例的54%；博士學位教師24人，占現(xiàn)任教師比例的65%，在學校已居前列，學院內(nèi)部已經(jīng)形成了一支高學歷、高水平、結構合理、層次適當?shù)囊灾星嗄杲處煘楣歉傻膶W術隊伍。深入調(diào)研，努力把握新形勢、新變化，詳細制訂了《化學工程學院2006-2010年學科建設與發(fā)展規(guī)劃》；全力響應學校領導布置，積極參與組織“國家工科化學 基地及化學化工學科十一五發(fā)展規(guī)劃”系列研討會，與理學院協(xié)力合作，共同完成《武漢理工大學“十一五”化學化工學科建設規(guī)劃》的撰寫工作，得到來訪的金涌院士的好評。

鄭化同志一貫兢兢業(yè)業(yè)，腳踏實地，工作勤奮，清正廉潔，2002年被評為校級標兵。2005年招收、指導博士、碩士人數(shù)共計博士1人、碩士8人。畢業(yè)博士、碩士研究生人數(shù)共計18人。指導研究生工作評價為優(yōu)秀。

鄭化同志主持和參與2項國家自然科學基金、4項浙江省重大科技攻關項目、4項湖北省科技攻關項目和10余項企業(yè)委托項目的研究，公開發(fā)表學術論文40余篇，其中SCI、EI收錄20余篇，獲授權發(fā)明專利3項。